Those who knew R. Höber's standard work on the physical chemistry of cells and tissues looked forward with great expectation to the first edition in English. This work has had six German editions between 1902 and 1926 and has been frequently called the bible of the physicochemistry of cells. The expectations are amply fulfilled by the English edition, which is by no means a condensation of the former publications but is an entirely new book, which covers the recent developments in the field of cellular physicochemistry. In the introduction, selected principles of physical chemistry are presented by D. L. Hitchcock in a concise and clear form, similar to that of his book, "Physical Chemistry for Students of Biology and Medicine" (Springfield. Ill., Charles C Thomas, Publisher, 1940). This part is supplemented by a comprehensive section by J. B. Bateman on the physicochemical properties of large molecules (micellae, films, membranes) and