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January 1947


Author Affiliations

Austin, Minn. Hormel Institute, University of Minnesota.
Minneapolis. Precision Contacts.

Arch Ophthalmol. 1947;37(1):89-90. doi:10.1001/archopht.1947.00890220096011

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To the Editor.  —Researches reported by Drs. Holt and Cogan (The Cornea: VIII. Permeability of the Excised Cornea, as Determined by Measurements of Impedance, Arch. Ophth.35:292 [March] 1946) have just come to our attention. The data in this paper, obtained through measurements of electrical impedance, definitely show that under the conditions used the corneal epithelium of excised beef corneas is virtually impermeable to various ions.In an earlier paper in the same series (The Cornea : II. Transfer of Water and Sodium Chloride by Hydrostatic Pressure Through the Excised Cornea, Arch. Ophth.27:696 [April] 1942) Cogan and Kinsey reported the results of osmotic studies concerning the semipermeability of the epithelium in excised cat corneas. In the latter paper, it was indicated in the authors' interpretation of the data that a difference in concentration of sodium chloride of approximately 0.03 per cent would be required to effect a transfer

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