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January 1948

CHEMOSURGICAL TREATMENT OF CANCER OF THE EYELID: A Microscopically Controlled Method of Excision

Author Affiliations

From the Department of Surgery, Dr. E. R. Schmidt, chief, State of Wisconsin General Hospital, and the McArdle Memorial Laboratory for Cancer Research, University of Wisconsin Medical School.

Arch Ophthalmol. 1948;39(1):43-59. doi:10.1001/archopht.1948.00900020046005

SELECTIVE destruction of accessible forms of cancer is attained, in effect, with the microscopic control of excision afforded by the chemosurgical technic. The development of the chemosurgical method in the laboratory1 and in the clinic2 has been described, as has the use ofthe method in the treatment of cancer in specific sites, such as the lip,3 nose4 and ear.5 The present article concerns the chemosurgical technic as applied to the treatment of cancer of the eyelid, and it presents the end results in 99 cases at the three year period and in 73 cases at the five year period.

TECHNIC  In the chemosurgical treatment of cancer of the eyelid, as in the treatment of cancer in other sites, the microscopic control is accomplished by means of a process consisting of the following steps: (1) in situ chemical fixation of the tissues suspected of being cancerous

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