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February 1948

AMBLYOPIA EX ANOPSIA: A New Concept of Its Mechanism and Treatment

Author Affiliations


Arch Ophthalmol. 1948;39(2):183-192. doi:10.1001/archopht.1948.00900020188005

THE PURPOSE of this paper is to present a new concept of the mechanism of amblyopia ex anopsia. It is hoped that the old theories will be reviewed and their present credence evaluated. Medical dictionaries and standard ophthalmologic texts perpetuate the definition of amblyopia ex anopsia as that amblyopia resulting from disuse of an otherwise normal eye. This point would be of academic importance only were not treatment of this condition involved which brings about improved results. This treatment hinges on acceptance of a new concept.

The following definition is offered as being closer to the actual conditions and therefore more tenable: Amblyopia ex anopsia is poor vision resulting from deviation of the visual axis from the fovea centralis to a point elsewhere on the retina where vision is less acute. It may be said that the greater the distance from the fovea, the less the visual acuity of this

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