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November 1948

LYMPHOSARCOMA OF THE EYELID: Report of Case, With Death in Forty Days

Author Affiliations

From the Institute of Ophthalmology of the Presbyterian Hospital in the City of New York.

Arch Ophthalmol. 1948;40(5):518-530. doi:10.1001/archopht.1948.00900030531005

LESS THAN 1 per cent of all lymphosarcomas originate in the region of the eye. When it does arise in the lid or the orbit, lymphosarcoma, although it infiltrates to a limited extent, tends to be a well circumscribed and slow-growing tumor; the other tissues of the body are not usually involved for many months or years. Lymphosarcoma also appears microscopically benign, with relatively well differentiated cells and few mitoses. Surgical removal may be followed by survival for many years, and irradiation has proved efficacious in ameliorating the disease for considerable periods. Cases of lymphosarcoma of the eyelid and/or orbit have recently been reported by Metivier,1 Cookson and MacRae,2 Michail,3 Tooke,4 Wheeler,5 Jensen,6 Siatto,7 Hine,8 Perera,9 Black10 and Rados.11

More commonly, lymphosarcoma begins in the cervical, axillary, mediastinal or mesenteric lymph nodes, or in the lymphoid tissue of the

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