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September 1949

ANISOCORIA: Attempted Induction by Unilateral Illumination

Author Affiliations

From the Institute of Ophthalmology, Presbyterian Hospital, and the Department of Ophthalmology, Columbia University College of Physicians and Surgeons.

Arch Ophthalmol. 1949;42(3):249-253. doi:10.1001/archopht.1949.00900050255003

THE VALUE of anisocoria as a diagnostic sign has been limited by reports of normal or physiologic anisocoria in as high as 40 per cent of all patients.1 Löwenstein's pupillographic method has eliminated a large number of cases of these so-called physiologic anisocorias through detailed cinematographic analysis under both static and dynamic conditions.2 In order to realize the potentialities of this method, and in order to place the proper value on the finding of anisocoria, it is necessary to delimit sharply that which may be physiologic from that which is pathologic. Toward this end the present study has been undertaken.

Several theories of the course of the afferent pupillary fibers have been proposed in attempts to explain various phenomena of the pupillary movements.3 The most generally accepted schema is that proposed by Behr,3c who stated the belief that the macular fibers from each retina have equal

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