KERATOCONUS is a localized conus-shaped, or mound-shaped, noninflammatory ectasia of the central portion of the cornea. The protruding area generally extends over the central half of the cornea and is always thinner than normal, but in some instances the conus may be eccentric. In some cases the deformity, after beginning to develop, remains stationary, without tendency to become worse; this condition is designated as abortive keratoconus. In other cases it remains stationary after developing to a more advanced stage; the patient is still able to obtain fairly good vision with the aid of ordinary glasses, although this correction may require the use of high cylinders.
The cornea of the conus may be reduced to one fifth of its normal thickness and in extreme cases may become still thinner. Occasionally Descemet's membrane and its endothelial lining rupture, and the aqueous passes into the parenchyma of the cornea with the subsequent development
CASTROVIEJO R. KERATOPLASTY IN TREATMENT OF KERATOCONUS. Arch Ophthalmol. 1949;42(6):776–800. doi:10.1001/archopht.1949.00900050787007
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