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September 1950

MALIGNANT MELANOMA OF THE UVEAL TRACT: Report of Case with Death Thirty Years After Enucleation

Author Affiliations

From the Department of Pathology, Missouri Baptist Hospital, St. Louis.

Arch Ophthalmol. 1950;44(3):381-394. doi:10.1001/archopht.1950.00910020390005

THE PRESENT case is of interest because of the extremely late postponement of death, a matter of some 30 years subsequent to initial enucleation for malignant melanoma of the eyeball. The case brings out a series of factors which appear to have considerable bearing on the apparent slowness of development of metastases and death. The case would suggest that the postoperative collapsed Tenon's capsule exerts a protective control of a residual optic nerve extension. Initial complications of glaucoma, rupture of the eyeball and probable necrosis of the initial neoplasm may have been important factors in the remarkable delay in the case.


History.  —T. D., a man aged 59, entered the hospital complaining of neuritis of a week's duration, intermittent in character, involving the thigh. The pain was severer while he was lying in bed and appeared to recede on walking. Pain had also appeared in the small

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