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January 1951


Author Affiliations


AMA Arch Ophthalmol. 1951;45(1):40-43. doi:10.1001/archopht.1951.01700010043005

RECENTLY at Cleveland City Hospital and at Lakeside Hospital there were observed a father and a daughter, both of whom had degenerative disease of the nervous system. The father showed both cerebellar and macular degeneration, and because of this unusual combination the cases are presented.

PRESENTATION OF CASES  The patient, a Negro aged 28 (Cleveland City Hospital no. 295-788), had been well until five years before admission, at which time he noted gradually failing vision. For two or three years he had noted slowly progressive ataxia, clumsiness and nervousness (tremors) and complained that people thought he was drunk because of his gait. There was a loss of weight of 36 pounds (16.3 Kg.) in the past five years. His occupation was that of molder in a foundry.His only other illness had been gonorrhea in 1948, which had been treated with penicillin.His mother died of unknown cause when he

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