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February 1951


Author Affiliations

From the Department of Ophthalmology, Columbia University College of Physicians and Surgeons.

AMA Arch Ophthalmol. 1951;45(2):139-148. doi:10.1001/archopht.1951.01700010144002

THERE are only a few scattered reports in the literature concerning the glycolytic activity of the cornea: Kohra1 demonstrated considerable aerobic and anaerobic activity in various layers of the rabbit cornea. He also noted that in the presence of ischemia, produced by the ligation of the ciliary arteries, the metabolism of the whole cornea remained unchanged but the metabolism of the endothelium fell rapidly. Thus he concluded that the endothelium is more susceptible to change than the other layers of the cornea. Similar results were reported by Fischer,2 though he failed to mention the type of experimental animal used or the technic employed. Herrmann and Hickman3 described extensive studies on corneal metabolism, but their interest centered mainly on the effect of mustard gas (2-chloroethyl sulfide) on the cornea; subsequently, any results they obtained concerning glycolysis of the normal cornea were only incidental to their prime objective. Furthermore,

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