THE PROBLEM of the origin of the ocular paralyses occurring in the course of migraine, referred to as ophthalmoplegic migraine, remains unsolved. Of the several concepts which have been proposed to explain them, that of cerebral aneurysm has received wide acceptance, though there has been little evidence to support it. In order to test the validity of the concept of cerebral aneurysm as a cause of ophthalmoplegic migraine, two patients with this condition were studied by means of arteriography. In neither instance was an aneurysm demonstrated.
REPORT OF CASES
—M. R. (J. H. no. R-54069). Recurrent pain in left side of head and left eye associated with ptosis of left eyelid, diplopia and partial oculomotor paralysis. Normal left internal carotid arteriogram on two occasions (1948 and 1950). No evidence of aneurysm to account for ophthalmoplegic migraine.The patient, a white woman aged 56, first appeared for relief on Oct. 26,
ALPERS BJ, YASKIN HE. PATHOGENESIS OF OPHTHALMOPLEGIC MIGRAINE. AMA Arch Ophthalmol. 1951;45(5):555–566. doi:10.1001/archopht.1951.01700010567008
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