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October 1951

BILATERAL TRANSVERSE OPTIC NEURITIS: Report of Two Cases with Cortisone Therapy

AMA Arch Ophthalmol. 1951;46(4):363-366. doi:10.1001/archopht.1951.01700020374001

SUDDEN binocular blindness occurring in an apparently healthy patient for no obvious reason is, fortunately, unusual. The purpose of this paper is to report on two such patients who were recently treated with cortisone and to discuss the diagnostic possibilities presented.


Case 1.  —E. L., a white man aged 30, an athletic coach, was admitted to the Veterans Administration Hospital, Jefferson Barracks, Mo., on June 18, 1950. At that time, he had been completely blind in both eyes for 24 hr.

History.  —On May 21, 1950, he received penicillin because of a "fever and sore throat." One week later vision was blurred in the left eye but then improved, and he was asymptomatic until June 15, when vision began to fail in both eyes and within two days had progressed to complete blindness. He had also experienced recent difficulty in urinating.Past and family histories were noncontributory.

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