CONCRETIONS form in the human body according to a definite law. Of first importance in their formation is a nucleus of a substance different from that to be deposited. The nucleus may consist of various substances, such as a foreign body or elements of the inflammatory process, e. g., mucus, desquamated epithelium, pigment, or micro-organisms. Around such a nucleus all or some constituents of the fluid in which the concretions form are deposited. The nucleus may play a primary or a secondary role in the pathogenesis of the concretion. The tears, being a watery fluid containing a small amount of solids and organic substances, preclude frequent formation of concretions because of these physical and chemical properties. However, tear stones, or dacryoliths, are encountered in the canaliculi and sometimes in the excretory ducts of the lacrimal gland. In the latter they occur as calcified lamellar formations of inflammatory origin. Calculi in
WEIZENBLATT S. PRIMARY CALCULUS OF THE LACRIMAL SAC: Report of a Case. AMA Arch Ophthalmol. 1952;48(1):61–65. doi:10.1001/archopht.1952.00920010064009
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