LIPEMIA retinalis was first described by Heyl1 in 1880. The pathognomonic quality of this phenomenon must certainly have impressed him when he wrote, "The moment my eye caught the details of the fundus, I saw the remarkable appearance which I shall endeavor to describe." Duke-Elder2 describes the condition as unmistakable. He states:
The change in colour of the retinal vessels is seen first in the periphery where they become hazy and slightly milky, and gradually the appearance spreads up towards the disc, the arteries and the veins in the average cases becoming flat and ribbon like and assuming a uniform appearance as if filled with milk, although in some cases a salmon-colour merging into cream is retained on or near the disc. In other cases the appearance is yellowish, but in all cases the light reflex becomes diffuse or is lost, and frequently yellowish-white stripes accompany both arteries
EVERETT WG. NONDIABETIC LIPEMIA RETINALIS: Report of a Case. AMA Arch Ophthalmol. 1952;48(6):712–715. doi:10.1001/archopht.1952.00920010724006
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