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May 1953

NUTRITIONAL DYSTROPHY OF CORNEAL EPITHELIUM: Preliminary Report of Patients Reacting Favorably to Vitamin Therapy

Author Affiliations


AMA Arch Ophthalmol. 1953;49(5):536-552. doi:10.1001/archopht.1953.00920020548005

LESIONS of the corneal epithelium vary in appearance from minute changes in J the individual epithelial cells to massive exfoliations of the whole covering, and in etiology from those with obscure and conjectural causes to those of proved and definite origin.

One of these lesions of the corneal epithelium of a nature and of an origin both obscure and conjectural has lately been observed with increased frequency in ophthalmological practice in the region around Lucena, Quezon Province, Philippines. It appears to be morphologically identical with the lesions of the corneal epithelium described by Ocampo,1 in 1941, as dystrophy of the corneal epithelium and with noninflammatory lesions of the corneal epithelium which appeared in great numbers in the Philippines during the war years from 1942 to 1944 inclusive.

The report is a clinical study of cases of this lesion seen in private practice within a four-year period and is an

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