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June 1953

FOCAL SCLERAL NECROSIS: A Late Sequel of Irradiation

Author Affiliations

From the Institute of Ophthalmology, Presbyterian Hospital.

AMA Arch Ophthalmol. 1953;49(6):633-636. doi:10.1001/archopht.1953.00920020646003

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RADIATION therapy about the eye is being employed by an increasing number of practitioners in an expanding category of conditions. It is only to be expected that an increase in the late complications of irradiation will be experienced. Radiation cataract, the commonest late complication, is known to every ophthalmologist. Its clinical and pathological characteristics have received a great deal of attention. In like manner, late skin changes and effects on bone growth are wellknown and easily recognized sequelae. The purpose of this paper is to report a less common late effect of application of radiation to the globe which presents a striking clinical appearance, namely, focal scleral necrosis. So far as could be determined, this sequela has not previously been described.


Case 1.  —J. G., a white man aged 38, had had a squamous-cell carcinoma of the right lower lid treated 18 years earlier with radium, 400

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