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October 1953

GLUCOSE UTILIZATION OF THE RETINAII. Influence of Various Hormones on the Glucose Utilization of the Retina

AMA Arch Ophthalmol. 1953;50(4):500-505. doi:10.1001/archopht.1953.00920030508011

IN A PREVIOUS paper1 the effects of various media on the glucose I tion of the retina were described. The present report deals with the influence of a variety of hormones (in vivo and in vitro) and of endocrine deficiencies on the glucose utilization of the retina. The retina of rats is a most suitable tissue for experiments on glucose utilization. It is easily removed in toto with little injury to its structure and is thin enough to permit diffusion of oxygen to the cells. In this respect it compares well with rat diaphragm.

It is known that the glucose metabolism of all tissues, with the exception of the brain, is either increased or inhibited by alterations of the hormonal balance. The brain, under most circumstances, is free of hormonal influence. The results of this study indicate that the glucose utilization of the retina is also independent of hormones