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September 1954

Retinal Circulation in Man and Animals.

AMA Arch Ophthalmol. 1954;52(3):495. doi:10.1001/archopht.1954.00920050497026

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The author has made preparations of the retinal vessels of various species of vertebrates after the injection of India ink into the circulation. The anatomy of the vascular tree and its development in the various species are compared in an effort to throw light on the anatomy and development of the vessels in man. Not only is the book of value because of its exposition of comparative anatomy, but considerable light is thrown on the pathogenesis of vascular disease in humans. For example, the author has found evidence that the development of retinal vessels in mammals is due to the presence of a factor or factors in the retina affecting the growth of the vessels. This factor is present in the extravascular tissue of the retina, chiefly in the neighborhood of the veins, so that its action is on the retinal veins predominantly. This finding may open up new approaches

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