EXOPHTHALMOS, with or without endocrine dysfunction, is an interesting disease manifestation which is poorly understood. Research on the association of endocrine dysfunction and exophthalmos has been stimulated by the advent of endocrine extracts, but, although much has been learned, the exact relationship is still not known. A unique case of rhythmical periodic unilateral exophthalmos of three years' duration is presented. The patient has been observed over a period of one and one-half years; extensive laboratory data were obtained, and clinical investigations with endocrine extracts were made. A brief résumé of some of the pertinent recent research on endocrine relationship to exophthalmos is included. A review of the medical literature has not revealed a similar case.
REPORT OF A CASE
—G. N., a 45-year-old white male veteran, was admitted to Veterans Administration Hospital, Cleveland, on Aug. 7, 1952, with the chief complaint of periodic edema of the left eyelids,
BENNETT JE. PERIODIC UNILATERAL EXOPHTHALMOS. AMA Arch Ophthalmol. 1954;52(5):683–698. doi:10.1001/archopht.1954.00920050685004
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