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March 1955

Quinnine Amblyopia: Report of a Case

Author Affiliations

St. Louis
From the Veterans Administration Hospital.

AMA Arch Ophthalmol. 1955;53(3):382-384. doi:10.1001/archopht.1955.00930010384008

The case of quinine amblyopia to be reported is considered of interest for several reasons. First, since the amblyopia occurred during a period of hospitalization for another condition, the opportunity arose for immediate, as well as continued, close ocular observation. Second, corticotropin (adrenocorticotropic hormone) was employed in the treatment of the quinine amblyopia.

REPORT OF CASE  A 48-year-old white man was admitted to the surgical service of the Veterans Administration Hospital, Jefferson Barracks, Mo., on Oct. 5, 1953, for treatment of a peripheral vascular disorder of the lower extremities, manifested by intermittent claudication and deficient pedal pulses.The patient was first seen by members of the ophthalmology department four days later, within 45 minutes after he developed sudden complete bilateral blindness, associated with dizziness, flushing, vomiting, tinnitus, and partial bilateral deafness. Review of the medication revealed that the patient had received a total of 0.8 gm. of oral quinine sulfate

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