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May 1955

Edrophonium (Tensilon) in Diagnosis of Ocular Myasthenia Gravis

Author Affiliations

Boston; New York
From the service of Dr. Truman L. Boyes and the Department of Research, New York Eye and Ear Infirmary.

AMA Arch Ophthalmol. 1955;53(5):718-719. doi:10.1001/archopht.1955.00930010726017

Myasthenia gravis frequently involves the extraocular muscles. Indeed, eye muscle involvement may be the earliest or the only sign of myasthenia gravis. The following history is presented to portray such a case and to call to the attention of the ophthalmologist a new drug for the diagnosis of myasthenia gravis thus far unknown to the ophthalmologic literature.

REPORT OF A CASE  J. C., a 16-year-old white boy, was first seen at the Outpatient Clinic of the New York Eye and Ear Infirmary on July 30, 1953, complaining of "bloodshot eyes." Visual acuity was recorded at 20/20 O. U. Physical examination revealed bilateral bulbar conjunctival injection with no other abnormalities: Lids, media and fundi were normal. Pupillary reactions were normal. No abnormality of the extraocular musculature was noted. The conjunctivitis cleared rapidly and completely on a local chemotherapeutic regimen. He was next seen on May 5, 1954, at which time he complained