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July 1955

Fixation of Corneal Grafts

Author Affiliations

Cardiff, Wales

AMA Arch Ophthalmol. 1955;54(1):1-5. doi:10.1001/archopht.1955.00930020003001

The subject of corneal transplantation has been of great interest to me for over 30 years, and it is perhaps appropriate that I should address you on a topic associated with that branch of ophthalmological work. I propose in the main to speak on the subject of the fixation of corneal grafts, with particular reference to circumscribed penetrating grafts.

It is now well established that a homoplastic corneal graft will unite readily with other corneal tissue if it is reasonably suited for its reception, and that such a graft can remain transparent. Many things, however, can happen to interfere with the success of a corneal graft, some of which are avoidable; and matters relating to the fixation of the graft are of considerable importance.

The objective in fixation is to maintain the cut surface of the graft in close apposition to its bed, until such time as union has taken