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July 1955

The Ocular Significance of Intracranial Calcium Deposits

Author Affiliations

From the Departments of Ophthalmology and Radiology, Children's Memorial Hospital and the Northwestern Uinversity Medical School.

AMA Arch Ophthalmol. 1955;54(1):77-91. doi:10.1001/archopht.1955.00930020079012

The importance of x-rays of the skull as a diagnostic aid in ophthalmological problems is now well established. These x-rays may be reported as normal except for the presence of calcium deposits in the substance or on the surface of the brain. In some cases these calcific deposits are considered as normal findings, whereas at other times they are of very definite ocular significance.

Calcification of the pineal gland (Figs. 1 and 2), calcium deposits in the choroid plexus of the lateral ventricle (Figs. 3-6), and osseous plaques in the falx cerebri (Fig. 7) may appear as normal findings. Calcifications of the Pacchionian granulations and calcifications in the hypophysis, although less common, may also be present normally.

Pathologically, intracranial calcifications may be seen in toxoplasmosis; Sturge-Weber syndrome; tuberous sclerosis; intracranial arterial aneurysms1; slow-growing tumors, such as gliomas and meningiomas,2 craniopharyngioma, and pituitary adenoma3; hypoparathyroidism3; arteriovenous

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