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July 1955

The Biologic Effects of Tobacco.

AMA Arch Ophthalmol. 1955;54(1):160. doi:10.1001/archopht.1955.00930020162019

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


To those who wish a comprehensive review of the evidence for and against smoking as a calculated risk to health, this book can be heartily recommended. There are many who still believe that tobacco is not an etiologic factor in any disease save possibly thromboangiitis obliterans. Statistical evidence from highly reliable sources, however, points toward the causal relationship between tobacco and cancer and some forms of cardiovascular disease. In spite of this evidence, the manufacturers of tobacco insist that smoking is harmless, although some rather naively, as Dr. Garland points out in his foreword, "advertise the use of filters to remove substances the toxicity of which they are unwilling to admit."

The chemistry and pharmacology of tobacco are thoroughly covered, and the evidence for the production of disease states in the cardiovascular system and the gastrointestinal tract is well documented, along with the influence of tobacco in the causation of

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