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August 1955

Facility of Flow Through the Trabecular Meshwork

Author Affiliations

From the Howe Laboratory of Ophthalmology, Harvard Medical School, and Massachusetts Eye and Ear Infirmary.

AMA Arch Ophthalmol. 1955;54(2):245-248. doi:10.1001/archopht.1955.00930020251012

This report presents one further detail in the investigation of factors which are responsible for the resistance to outflow of aqueous humor from the eye. One portion of this study which has already been reported was concerned with tonographic determination of facility and rate of outflow of aqueous humor in patients *; another portion has been experimental, concerned with measurement of facility of outflow from enucleated eyes, both normal and glaucomatous.†

It has been shown that the facility of outflow from enucleated eyes differs by only about 10% from that found in vivo by tonography.4 Furthermore, the external two-thirds of the perilimbal sclera, with its included portions of the outflow channels, can be removed from enucleated normal human eyes without appreciably increasing the facility of outflow.5 It has appeared from these findings that the principal anatomic resistance to flow is to be found in the immediate neighborhood of Schlemm's