Both benign and malignant tumors of the lacrimal sac are uncommon. Prior to 1938 Penman and Wolff1 were able to find only 64 cases of lacrimal sac tumor described and reported in the world literature. Ashton, Choyce, and Fison2 have stated that there were 73 such tumors reported up until 1950. In 1952 Duke-Elder3 described an additional 60 cases of tumor of the lacrimal sac. However, 26 of these were granulomas. When these 26 cases are disregarded, the total number of cases of true neoplasms of the lacrimal sac is now in excess of 100.
It appears that epithelial tumors are slightly commoner than nonepithelial tumors. It is probable that the diagnoses of "carcinoma," "malignant papilloma," and "epithelioma" represent different stages of cylindrical-cell carcinoma and that such tumors form about 50% of all reported cases.
In most cases of lacrimal sac tumor described in the literature the
DAVIS RJ. Epidermoid Carcinoma of the Lacrimal Sac. AMA Arch Ophthalmol. 1956;55(1):21–22. doi:10.1001/archopht.1956.00930030023004
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