It has been shown experimentally that low-voltage x-radiation in appropriate doses can inhibit new-vessel growth into the cornea (Scheie and associates,3 1950; Michaelson and associates,2 1954). Experimental work has shown that such x-radiation fails to prevent new-vessel growth (Michaelson and associates, 1954). In the inhibition experiments the radiation was given shortly after commencement of active neovascularization. In the prevention experiments the radiation was given some time before the onset of the experimentally produced vascularization or coincidentally with its onset. Reports on the regression effect of radiation on experimentally produced vascularization are not available. By this is meant the effect of the radiation on established corneal vessels after the factor stimulating the presence of these vessels has ceased to be operative. It is of some practical importance to know whether such a regressive influence exists in order, for example, to know whether it is worth while radiating a vascularized
MICHAELSON IC, SCHREIBER H. Influence of Low-Voltage X-Radiation on Regression of Established Corneal Vessels. AMA Arch Ophthalmol. 1956;55(1):48–51. doi:10.1001/archopht.1956.00930030050010
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