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February 1956

Perfusion Studies on the Outflow of Aqueous Humor in Human Eyes

Author Affiliations

Ghent, Belgium
Researcher of the National Funds for Scientific Research (Dr. Rabaey).; From the Ophthalmological Clinic of the University of Ghent; Director, Prof. J. François, M.D.

AMA Arch Ophthalmol. 1956;55(2):193-204. doi:10.1001/archopht.1956.00930030195005

The tonography studies of Grant * have shown clinically the importance of the outflow of the aqueous humor. It is the decrease of the outflow in wide-angle glaucoma that is especially interesting.

Normally, the average value for outflow of aqueous humor per millimeter Hg per minute (C) is 0.24 cu. mm. according to Kronfeld,11 0.23 cu. mm. according to Grant9 and Mansheim,12 and 0.22 cu. mm. according to Weekers and Prijot.18

The resistance to the outflow of aqueous humor (R) is inversely proportional to the value of C, that is, 1/C. According to Weekers, Watillon, de Rudder, and Lustin (1955), the average values of R are 3.7 for ages less than 35 years, 4 for ages between 35 and 55, and 4 for ages past 55.

In wide-angle glaucoma, Weekers and Prijot † found in a series of eyes the ocular tension of which was less