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June 1956

Diurnal Changes in Eosinophile Count: Comparison with Changes in Intraocular Pressure, Tonographic Values, and Aqueous Veins

Author Affiliations

From the Department of Ophthalmology, University of Cincinnati College of Medicine.; Assistant of the Clinica Oculistica, Università di Cagliari; former research assistant, University Eye Clinic (Dr. Cambiaggi).

AMA Arch Ophthalmol. 1956;55(6):765-778. doi:10.1001/archopht.1956.00930030769002

In the past, considerable emphasis has been placed on the conflict between the neurovascular and the mechanical theory of glaucoma. According to the first theory, primary glaucoma arises from a disturbance of the neurovascular system of the eye, whereas according to the mechanical theory it depends on alterations in the mechanics of aqueous humor flow. This conflict is particularly evident in congestive glaucoma (narrow-angle glaucoma), whereas in chronic simple glaucoma (wide-angle glaucoma) the two theories are more easily reconciled.

The detection of the aqueous veins (1941) and the introduction of tonography (1950), giving glaucoma research a new impetus, have led most authorities to agree that in chronic simple glaucoma an obstruction, type unknown, is present somewhere between the anterior chamber and the deep or superficial scleral veins. The immediate cause of this obstruction is most likely either a vasoconstriction or a sclerosis of the angle or adjacent structures. The ultimate