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June 1956

Aqueous Humor Outflow: An Experimental Study Using Radiopaque Materials: 1. Paracentesis Technique, Response Evoked, and Demonstration of Pathway of Outflow

Author Affiliations

Ann Arbor, Mich.

AMA Arch Ophthalmol. 1956;55(6):792-799. doi:10.1001/archopht.1956.00930030796004

In 1941 Ascher * first detected aqueous veins biomicroscopically. They have since been photographed † and observed in experimental animals‡ Goldman § concluded that these veins, connecting the intrascleral venous meshwork with the episcleral venous meshwork, contained aqueous by the observation that they remained colorless after intravenous administration of the dye fluorescein sodium (uranin). The episcleral vessels, however, contained blood and took on a yellowishgreen tint. This same investigator repeated Seidel's (1923) rabbit experiments by injecting India ink into the anterior chamber of a sarcomatous human eye. He reported that the episcleral vessels did not change color but that the aqueous veins were tinted black. It was felt that this demonstrated the communication of the anterior chamber with the aqueous veins.

More recent work by Greaves and Perkins,9 however, has revealed a failure of suspensions of India ink to appear in the aqueous veins of rabbits after injection into the