Changes in Aqueous Flow and Blood-Aqueous Barrier After Hydrochloric Acid Burns to the Eye

Introduction  In a previous communication from this laboratory¹ it was demonstrated that the ascorbic acid and lactate concentrations in the anterior aqueous humor of rabbits decrease after onset of hydrochloric acid injury to the cornea. The concentration of these materials remains lower than normal for three to four days. It was demonstrated that there was no increase in the rate of utilization of these substances by the anatomic components of the anterior segment of the injured eye. It was therefore concluded that the data were indirect evidence that an increase in permeability of the iris vessels occurred as a result of the acid injury.It is the purpose of the present work to show by more direct means that an increase in permeability of the iris vessels as well as an increase in the rate of flow of the aqueous humor occurs in the rabbit eye after hydrochloric acid