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April 1957

Retinitis Pigmentosa: A Histopathologic Study with a New Technique

Author Affiliations

Ann Arbor, Mich.
From the Laboratory of Neuropathology and Neuroophthalmology and from the Department of Ophthalmology of the University of Michigan Hospital.

AMA Arch Ophthalmol. 1957;57(4):539-553. doi:10.1001/archopht.1957.00930050551008

Primary pigmentary degeneration of the retina is considered a heredodegenerative disease of the eye. It typically involves both eyes, begins in the region of the equator, and proceeds posteriorly. The present knowledge of the pathology of this clinical entity is composed of the findings of a large number of investigators (Landolt,1 Wagenmann,2 Lister,3 Stock,4 Leber,5 Ginsberg,6 Gonin,7 Suganumba,8 Verhoeff,9 Ascher,10 Cogan,11 among others). The main findings of these authors are very adequately summarized in the textbooks of Duke-Elder,12 Friedenwald,13 and Elwyn.14

The present paper is a report of some new pathologic details which were observed histologically in the eyes of an advanced case of primary pigmentary degeneration, which were stained with the silver carbonate techniques of del Rio Hortega.

Report of Case  A male patient was first seen in 1928 by Dr. F. B. Fralick, chairman

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