The appearance of metastatic carcinoma in the orbit from a remote source is of such unusual occurrence as to excite special interest. Reports of metastases from adenocarcinoma of the kidney parenchyma have been particularly infrequent. One case to be presented represents a common manifestation of metastatic disease in the orbit by its invasions from the sinus with functional loss of the eye. The second case represents an unusual manifestation by its appearance in the skin on the orbital margin.
Renal carcinoma is known by a variety of names: hypernephroma, carcinoma, adenocarcinoma of the parenchyma, Grawitz tumor, and clear-cell carcinoma. Its curious characteristics and fickle natural history account for this varied nomenclature and the continued confusion in the literature over its origin and identification. It may be either slowly or rapidly growing. It is locally invasive and characteristically metastasizes via the blood stream because of its tendency to invade the veins
VAN ARNAM CE, FINE M. Orbital Metastasis of Renal Carcinoma. AMA Arch Ophthalmol. 1957;57(5):694–701. doi:10.1001/archopht.1957.00930050706010
Customize your JAMA Network experience by selecting one or more topics from the list below.