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October 1958

Polyarteritis Nodosa with Ophthalmic and Neurological Complications

Author Affiliations

York, England; Leeds, England
County Hospital, York (Dr. Sheehan); Department of Neuropathology, University of Leeds (Dr. Harriman); Research Assistant to Department of Neurology, General Infirmary, Leeds (Dr. Bradshaw).

AMA Arch Ophthalmol. 1958;60(4):537-547. doi:10.1001/archopht.1958.00940080555003

The purpose of this paper is to report on a case of polyarteritis nodosa which has some unusual features of special ophthalmic and neurological interest.

Report of a Case  A woman was aged 35 years at death. At the age of 11 she had rheumatic fever; at 18 she had an appendectomy, and at 30, in her second pregnancy, she developed hypertensive toxemia necessitating termination during the 30th week. She had no other illnesses. Family history was not significant.Since the age of 30 she had suffered from nocturnal cramps in the limbs of a myoclonic type and some loss of flesh on the left side of her face. At the age of 32 she developed abdominal pain in the epigastrium and vomiting of bilious fluid, which settled within a few weeks, and subsequently she had alternating periods of diarrhea and constipation. She lost weight. Soon afterward she was admitted

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