Following the discovery of human congenital toxoplasmosis, in 1937, it was suspected by ophthalmologists and other investigators that Toxoplasma might be a cause of acquired chorioretinitis. It was not until 1954 that Jacobs1 reported the isolation of these organisms from the enucleated eye of an adult. The strain isolated from his patient was of high virulence for laboratory animals, closely resembling the well-known RH strain.
In this paper we report the characteristics of a strain exhibiting low virulence for animals which was recovered from the enucleated eye of a 20-year-old youth. A diagnosis of congenital ocular toxoplasmosis had been made on this patient eight years previously.
Report of a Case
A white boy aged 12 years was first seen in March, 1948, because he had sudden diminution of vision in his good left eye. During a routine clinic examination at the age of 1½ years he had been
HOGAN MJ, ZWEIGART PA, LEWIS A. Recovery of Toxoplasma from a Human Eye. AMA Arch Ophthalmol. 1958;60(4):548–554. doi:10.1001/archopht.1958.00940080566004