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Article
November 1958

The Fine Structure of the Lens Epithelium: An Electron Microscopic Study

Author Affiliations

Bethesda, Md.
From the Ophthalmology Branch, National Institute of Neurological Diseases and Blindness, National Institutes of Health, Public Health Service, U. S. Department of Health, Education, and Welfare.

AMA Arch Ophthalmol. 1958;60(5):868-879. doi:10.1001/archopht.1958.00940080888007
Abstract

Introduction  Improved techniques of fixation and ultrathin sectioning in electron microscopy now permit the study of biological tissue on a nearly molecular level and in its natural milieu; as a result, a great amount of new information is available to cytologists.The lens epithelium was selected for the present investigation because of its important role in the biology of both the normal and the pathological lens. A variety of functions is combined within this monolayered structure, as can be presumed from the morphological differentiation into a "resting" (central) zone and a "germinative" (equatorial) zone. Another interesting aspect is that the mature lens, although devoid of any nervous and vascular supply, constitutes an organelle with continuous cytokinetic activity.Previous electron microscopic studies on the lens have been primarily concerned with the capsule (Bahr,1 Bairati and Grignolo,2 and Grignolo3), zonular fibers (Böke and Lindner4), and lens fibers (François,

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