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December 1958

Metastatic Carcinoma of the Iris and Ciliary Body

Author Affiliations

From the Wilmer Ophthalmological Institute of The Johns Hopkins University and Hospital.

AMA Arch Ophthalmol. 1958;60(6):1092-1103. doi:10.1001/archopht.1958.00940081112016

Introduction  Metastatic carcinoma to the anterior ocular segment occurs infrequently. Middleton5 in 1952 found 31 cases in the literature and added 2 cases of his own. Mayer and Ray4 in 1955 added one more case, and Bonamour and Bonnet1 in 1956 added the last-reported case, bringing the total of such cases to 35.The difficulties encountered in the clinical diagnosis of this condition plus the rarity of occurrence of the lesion itself prompts us to report the following four cases.

Report of Cases 

Case 1.  —A 49-year-old Negro man entered a local hospital on Sept. 10, 1956, with the chief complaint of a constant cutting pain between his shoulder blades and sternum of four weeks' duration. There had been a weight loss of 30 lb. over an indefinite period.Initial examination revealed a malnourished, chronically ill Negro man. Positive findings included a lag on inspiration of the

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