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February 1959

Practical Management of Granulomatous Chorioretinitis

Author Affiliations

U. S. Army; U. S. N.

AMA Arch Ophthalmol. 1959;61(2):226-229. doi:10.1001/archopht.1959.00940090228005

Since the discovery of Toxoplasma in lesions of chorioretinitis, its importance as a causative agent is being increasingly recognized. The criteria for its diagnosis are (1) compatible ocular picture, (2) positive Feldman-Sabin dye test in a minimum titer of 1:64, (3) positive toxoplasmin skin test, (4) exclusion of other granulomatous disease, and (5) a favorable response to antitoxoplasmic therapy.1 Of these criteria, only the performance of the dye test presents difficulties for the practicing ophthalmologist. The technical difficulties of the test enable only a few laboratories to perform it in limited quantities, and the results, therefore, are not available to most physicians within a few days. By relying on the toxoplasmin skin test, however, a presumptive diagnosis can be entertained and early treatment begun.

Presented here is a review of consecutive cases of granulomatous chorioretinitis seen by us from January, 1956, to March, 1958. The evaluation consisted of a

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