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This is a survey of the field of physiology and seeks to answer questions of interest to investigators, teachers, administrators, editors, and grantors who have a common interest in this branch of basic science. It represents an enormous expenditure of time and effort and will be of value to ophthalmologists interested in research in fields of ocular physiology, particularly if they are administrators. The author has viewed the results of his labors far too pessimistically when he states, "Fondly conceived as another Flexner report, it lacked the Flexner to produce it."