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May 1959

Recurrent Intraocular Hemorrhage in Young Adults (Eales' Disease): Treatment with Continuous Subconjunctival Therapy with Hydrocortisone

Author Affiliations

From the Department of Ophthalmology, University of Toronto, Toronto General Hospital, and Sunnybrook Hospital, Department of Veterans' Affairs.

AMA Arch Ophthalmol. 1959;61(5):745-754. doi:10.1001/archopht.1959.00940090747011

In 1954, I1 reported my observations on 31 cases of recurrent intraocular hemorrhage in young adults, an entity commonly known by the name of Eales' disease but probably more correctly called retinal periphlebitis. The typical case usually occurs in an apparently healthy young man, with a sudden painless blurring of vision on awakening in the morning. The hemorrhages are characteristically in the periphery of the retina and are associated with the retinal veins, which show marked perivascular exudation, varying from a narrow path of sheathing to extensive exudation. As a rule, the veins tend to be dilated, but in some cases they may be beaded or varicose over short segments of their course. The hemorrhages are usually confined to the retina at the beginning, but it is only a matter of time until one occurs which is of sufficient magnitude to burst through the internal limiting membrane into the

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