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September 1959

Postmortem Chemistry of the Vitreous Body in Man

AMA Arch Ophthalmol. 1959;62(3):356-363. doi:10.1001/archopht.1959.04220030012003

While there is information on the chemistry of the vitreous body (VB) in various animals,1-12,14,15,24-29,31 reports on chemical constituents of the human VB are virtually nonexistent except for a few data on enucleated eyes.3,16 Since material from human eyes during life is not available, it was thought of interest to investigate the VB of human cadavers in the course of studies on postmortem chemistry.19-23

Materials and Methods  Autopsies performed on 211 male bodies of an average age of 58 years examined about nine hours after death on the average were selected on the basis of minimum pathology or changes unrelated to the metabolism of substances under investigation. About 2 to 5 ml. of VB pooled from both eyes were obtained at time of autopsy by a 10 cc. syringe and 20 gauge needle through puncture of the eyeball at the external canthus. Cerebrospinal fluid (CSF) was removed as

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