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November 1959

Electroretinographic Measurement of the Spectral Sensitivity in Albinos, Caucasians, and Negroes

Author Affiliations

Bethesda, Md.
Visiting Scientist from the William G. Kerckhoff-Institut der Max-Planck-Gesellschaft, Bad Nauheim, Germany (Dr. Dodt).; From the Ophthalmology Branch, National Institute of Neurological Diseases and Blindness, National Institutes of Health, Public Health Service, U. S. Department of Health, Education, and Welfare.

AMA Arch Ophthalmol. 1959;62(5):795-803. doi:10.1001/archopht.1959.04220050057010

The albino's pupil appears red when the eye is diffusely illuminated, but when no light is transmitted through the iris and sclera the pupil appears black.1 The degree of fundus pigmentation is important not only when there is diascleral exposure, but also when all of the light enters the eye through the pupil, since light diffusely reflected from the fundus indirectly stimulates a wide area of photoreceptors.

It has been shown by measurement of the electroretinographic threshold in albino rabbits that the effect of scattered light from the red end of the spectrum far exceeds that from the blue end, and thereby greatly modifies the shape of the electroretinographic spectral sensitivity curve.2,3 The Purpose of this investigation was to extend such observations to include a study of the influence of varying amounts of retinal pigmentation in humans. This seems especially desirable since the method of cone electroretinography with

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