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November 1959

Bilateral Melanoma of the Choroid Associated with Leukemia and Meningioma

AMA Arch Ophthalmol. 1959;62(5):889-893. doi:10.1001/archopht.1959.04220050149023

The bilateral occurrence of a malignant melanoma of the uveal tract is of sufficient rarity to warrant a short report. Schies-Gemuseus1 has reported such a case as did Landsburg.2 Carter3 reported bilateral malignant melanomata of the irides. Similar cases were seen by Dixon4 and Hirschberg.5 However, in all these cases the tumor in the fellow eye was not proven histologically. The first proven bilateral case was that of Shine6 in which the choroid and iris were involved respectively; Cordes and Cook7 reported a similar case with histological proof. A. B. Reese,8 in his book, mentions having seen one such case of bilateral melanomata of the uveal tract. In Landsburg's case, the melanomata occurred simultaneously. In Dixon's case, the interval was six months; in Hirschberg's case, one year; and in Shine's case, three years. Cordes and Cook's case was interesting in that, in