For several years we have recognized an unusual eye reaction in some children after eye muscle surgery. The reaction appears unexpectedly, most often about one week after the operation. It is characterized by discomfort and itchiness of the eye, chemosis and hyperemia of the conjunctiva, and edema of the eyelids. The symptoms usually subside in 12 to 48 hours. At times the eye signs appear within 24 hours after operation. In these cases the reaction frequently is more intense and may persist for a week if untreated.We have been unable to relate the reaction to infection, to the amount or type of operation, or to the use of local eye medication.To study the possibility that the eye reaction was due to an unusual response to catgut, simultaneous observations were made of eye reaction and the cutaneous response to catgut inserted at the time of operation in 219
APT L, COSTENBADER FD, PARKS MM, ALBERT DG. Catgut Allergy in Eye Muscle Surgery: I. Correlation of Eye Reaction and Skin Test Using Plain Catgut. AMA Arch Ophthalmol. 1960;63(1):30–35. doi:10.1001/archopht.1960.00950020032004
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