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January 1960

Malignant Melanoma or Retinoblastoma in an Adult: A Differential Diagnostic Problem

Author Affiliations

From the Departments of Pathology of The Brooklyn Hospital and the Brooklyn Eye and Ear Hospital.

AMA Arch Ophthalmol. 1960;63(1):70-76. doi:10.1001/archopht.1960.00950020072011

The anatomical identification of a white intraocular tumor in an adult can occasionally be very difficult. Accurate recognition of the nature of the lesion is, of course, important from the standpoint of prognosis, but such cases also have academic interest as a diagnostic challenge especially to the pathologist. Some of the differential diagnostic features that may be presented under such circumstances are shown in an illustrative case. As our title indicates, one of the chief considerations suggested by that case is the possible occurrence of retinoblastoma in adult life.

Report of Case  A 46-year-old man noticed gradual diminution of vision in the right eye beginning about November, 1956. By July, 1957, there was no vision in that eye, but the patient did not seek medical attention until the eye became painful in 1958. He was first seen on the service of Dr. Michael J. Buonaguro at the Brooklyn Eye and

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