Although splitting of the layers of the retina has been noted clinically and pathologically for many years, there have been few reports correlating these two observations. François and Rabaey1 reported a clinicopathological case of retinal cyst in 1953, the same year in which Teng and Katzin2 reported their observations on peripheral retinal cysts in 170 eye bank eyes. The term, retinoschisis, to denote a more extensive separation of the layers of the sensory retina, seems preferable to retinal cyst which does not differentiate large areas of splitting from small areas of peripheral cystoid changes.
Retinoschisis is more commonly seen in males of the fourth and fifth decades and tends to be bilateral. The disease is usually asymptomatic and is frequently discovered incidentally during a complete eye examination. The separation of the retinal layers begins close to the ora serrata; it extends posteriorly but rarely to the macula. At
CURTIN VT, NORTON EWD, SMITH TR. Pathological Confirmation of Retinoschisis: A Case Report. AMA Arch Ophthalmol. 1960;63(6):978–983. doi:10.1001/archopht.1960.00950020980012
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