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January 1961

Retinal Vein Occlusion: An Experimental Study

Author Affiliations

New York
Department of Ophthalmology, New York University-Bellevue Medical Center.; Special Fellow, U.S. Public Health Service, National Institute of Neurological Diseases and Blindness.

Arch Ophthalmol. 1961;65(1):2-10. doi:10.1001/archopht.1961.01840020004002

Introduction  In this study a method for the production of venous occlusion in the retinal veins of the cat will be described. Changes so produced will be reported. Becker and Post1 have described a method for the production of experimental venous occlusion in the cat using an intraocular electrode. These workers described changes in eyes in which venous occlusion had been produced. They stated "Serial sections of such eyes revealed hemorrhages, exudates and venous thrombi which became organized and recanalized." With the availability of the retinal light coagulator of Meyer-Schwickerath, Dr. George N. Wise suggested its use in experimental venous occlusion.

Material and Methods  The animals were healthy cats weighing 2-2.5 kg. The pupils were maximally dilated by repeated instillation of atropine sulfate 1%. Intraperitoneal pentobarbital (Nembutal) gave satisfactory anesthesia. The lids and nictitating membrane were retracted with a suitable speculum. It is important that as little time as

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