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May 1961

Orbital Reaction to Sponge (Ivalon) Implant

Author Affiliations

Howe Laboratory of Ophthalmology, Harvard University Medical School, Massachusetts Eye and Ear Infirmary.

Arch Ophthalmol. 1961;65(5):646-647. doi:10.1001/archopht.1961.01840020648007

The following case is thought to be of interest in showing a foreign body reaction in the orbit to a sponge-type of prosthesis (Ivalon). The reaction was not apparent until 2 years after enucleation; it then suggested clinically a recurrence of the retinoblastoma for which the eye had been originally removed. Although similar reactions have been noted in tissues elsewhere in the body, this appears to be the first description of the histologic changes in the orbit induced by this material.

Report of Case  The patient was a 3-year-old girl who had had the right eye removed for retinoblastoma at the age of 3 months. The operative record noted a routine enucleation procedure with implant of a No. 18 glass ball into the muscle cone and a muscle-to-muscle suture by No. 4 catgut, covered by conjunctiva.Two weeks after this initial surgery the glass ball extruded and the patient was

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