[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 18.207.255.49. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
June 1961

Enzymatic Zonulolysis as an Aid in Cataract Surgery: A Follow-Up Report on 432 Cases with 491 Additional Cases

Author Affiliations

Upper Darby, Pa.; Scranton, Pa.; Wilkes-Barre, Pa.; Philadelphia, Pa.; Scranton, Pa.

Arch Ophthalmol. 1961;65(6):801-804. doi:10.1001/archopht.1961.01840020803009
Abstract

One year ago we reported 432 cases of cataract extraction in which α-chymotrypsin was used to aid in zonulolysis.1 We are now reporting its use in 491 additional cases performed by the same authors in the same institutions. Eighty-eight of these were performed by the resident surgeons of Wills Eye Hospital under close supervision. Our results have again been tabulated according to the questionnaire on α-chymotrypsin suggested by the Committee on Alpha-Chymotrypsin of the American Academy of Ophthalmology and Otolaryngology.

The following 4 preparations of α-chymotrypsin were used:

1. Alpha Chymar (Armour Laboratories, Kankakee, Ill.)

2. Quimotrase (PEVYA Laboratories, Barcelona, Spain)

3. Zolyse (Alcon Laboratories, Fort Worth, Texas)

4. Chymexon (Schieffelin and Co., New York)

We were not aware of any difference in the action of these products. We have agreed on a 1:5,000 solution because we believe this concentration assures us of the best result. We have not

×