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October 1961

Intraocular Hodgkin's Disease

Author Affiliations

Los Angeles

Arch Ophthalmol. 1961;66(4):477-482. doi:10.1001/archopht.1961.00960010479007

Introduction  Hodgkin's disease is a progressive neoplastic disease involving the lymph nodes and lymphatic system early and all organ systems late. It is classified as a lymphoma.1The diagnosis is suspected from the clinical characteristics of the disease, consisting of a painless and progressive swelling of the lymph nodes often in association with a fever called Pel-Ebstein fever. Pruritus may be an annoying symptom. Laboratory findings may be normal, but there is often an associated eosinophilia and an elevated sedimentation rate. The diagnosis is confirmed by biopsy of an involved lymph node and in finding a characteristic giant cell called the Dorothy Reed-Sternberg cell.2This case presentation is of specific interest to ophthalmologists. The patient had an intractable uveitis for 18 months. Then, it was discovered she had Hodgkin's disease.

Report of Case 

History.  —The patient was a 73-year-old white female who, in February, 1958, stated that she